Lancet, Neurology paper released “Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington’s disease: a retrospective cohort analysis”.
Authors: Lauren M Byrne, MRes, Filipe B Rodrigues, MD, Prof Kaj Blennow, PhD, Prof Alexandra Durr, PhD, Prof Blair R Leavitt, PhD, Prof Raymund A C Roos, PhD, Rachael I Scahill, PhD, Prof Sarah J Tabrizi, PhD, Prof Henrik Zetterberg, PhD, Prof Douglas Langbehn, PhD, Dr Edward J Wild, PhD.
Background:
Blood biomarkers of neuronal damage could facilitate clinical management of and therapeutic development for Huntington’s disease. We investigated whether neurofilament light protein NfL (also known as NF-L) in blood is a potential prognostic marker of neurodegeneration in patients with Huntington’s disease.